Advertisement

We need your help now

Support from readers like you keeps The Journal open.

You are visiting us because we have something you value. Independent, unbiased news that tells the truth. Advertising revenue goes some way to support our mission, but this year it has not been enough.

If you've seen value in our reporting, please contribute what you can, so we can continue to produce accurate and meaningful journalism. For everyone who needs it.

Damian Dovarganes/AP/Press Association Images

This HIV vaccine looks promising

The vaccine appears to have completely cleared the virus from monkeys.

RESEARCHERS IN THE US have reported significant progress in their development of a vaccine against HIV.

The Oregon Health and Science University’s Vaccine and Gene Therapy Institute published an update in the journal Nature today, outlining latest test results which show that their vaccine appears to completely clear the virus from in monkeys.

The scientists have used a non-human primate form of HIV – called simian immunodeficiency virus (SIV) – which causes AIDS in monkeys in their experiments but they hope a HIV-form of the vaccine candidate can be tested on humans soon.

“To date, HIV infection has only been cured in a very small number of highly-publicised but unusual clinical cases in which HIV-infected individuals were treated with anti-viral medicines very early after the onset of infection or received a stem cell transplant to combat cancer,” said Louis Picker, associate director of the OHSU Vaccine and Gene Therapy Institute.

“This latest research suggests that certain immune responses elicited by a new vaccine may also have the ability to completely remove HIV from the body.”

Picker’s lab uses cytomegalovirus, or CMV, a common virus already carried by a large percentage of the population in its candidate vaccine. The researchers found that the engineered CMV which expressed SIV proteins can generate and maintain cells that search out and destroy SIV-infected cells.

According to Science Daily, about 50 percent of monkeys given highly pathogenic SIV after being vaccinated with this vaccine became infected with SIV but over time eliminated all trace of SIV from the body.

In effect, the hunters of the body were provided with a much better targeting system and better weapons to help them find and destroy an elusive enemy.

“Through this method we were able to teach the monkey’s body to better ‘prepare its defences’ to combat the disease,” explained Picker.

“Our vaccine mobilised a T-cell response that was able to overtake the SIV invaders in 50 per cent of the cases treated. Moreover, in those cases with a positive response, our testing suggests SIV was banished from the host. We are hopeful that pairing our modified CMV vector with HIV will lead to a similar result in humans.”

Pics: Soyuz wanna see a spaceship? Here’s one that landed this morning in Kazakhstan

More: Cheating makes you feel good – once you don’t get caught

Readers like you are keeping these stories free for everyone...
A mix of advertising and supporting contributions helps keep paywalls away from valuable information like this article. Over 5,000 readers like you have already stepped up and support us with a monthly payment or a once-off donation.

Close
25 Comments
    Install the app to use these features.
    Mute booby sandwiches
    Favourite booby sandwiches
    Report
    May 20th 2017, 8:07 PM

    fantastic news, the economy is booming. a shinner will be along shortly now with doom and gloom LOL

    148
    Install the app to use these features.
    Mute cholly appleseed
    Favourite cholly appleseed
    Report
    May 20th 2017, 10:27 PM

    @Jayo Breathneach: the property crash wasn’t caused by outside investors. It was by people taking out too big mortgages. Maybe you move in the wrong circles if you can’t afford a house

    38
    Install the app to use these features.
    Mute John Clair
    Favourite John Clair
    Report
    May 20th 2017, 9:29 PM

    the issue i have is that the SDZ rules have been thrown at the window…I live in Adamstown and I am happy to see development start again Im dissaappointed that the amenities like the parks and town centre are on hold. It worries me that they will never be built. Even the PR piece about the community centre is kind of false…what is being built is a sports hall for the secondary school which can act as a community center.
    It worries me that Adamstown will turn into another Lucan where people have to travel to do things as all that was built in Lucan was houses.

    Adamstown was supposed to be a self contained town where all amenties would be near by and within walking distance. Now Its just going to become another Housing estate

    126
    Install the app to use these features.
    Mute Jarlath Murphy
    Favourite Jarlath Murphy
    Report
    May 20th 2017, 9:24 PM

    No housing for 10 yrs, creates a drought! Available housing gifted to vulture funds at exchequers expense. Housing shortage creates property price bubble, banks balance sheets improves exponentially! Cheerleaders of austerity clap themselves on the back, while young people forced to rent for extended period to gather sufficient funds for a deposit! Same aul Fianna Gael, keep pretending the recovery is going! Check out the debt clock, 200 billions and counting!

    60
    Install the app to use these features.
    Mute Gerry Glynn
    Favourite Gerry Glynn
    Report
    May 20th 2017, 8:16 PM

    All the lost money is back in play .who lifted the flooring boards

    49
    Install the app to use these features.
    Mute Dark Knight
    Favourite Dark Knight
    Report
    May 20th 2017, 10:08 PM

    @Jayo Breathneach: so many people just comment for the sake of making noise. You will be preaching again shortly about the lack of available houses. There is no bubble, we are well short of peak price of the boom and if we’re to going into a bubble we would be adding another 10% to that due to population increase.
    The problem isn’t housing, we have plenty of empty houses in this country. The problem is the total failure by the government to build sustainable economies outside of Dublin. If you talk to most people who moved from different parts of the island to Dublin for work, they would love to move back home but there are no jobs in their field outside Dublin. Invest in areas outside Dublin, people can start moving into empty homes down the country and puts less pressure on rents and the price of houses in Dublin

    44
    Install the app to use these features.
    Mute kevin
    Favourite kevin
    Report
    May 20th 2017, 11:24 PM

    @Dark Knight: move the capital to the midlands?

    13
    Install the app to use these features.
    Mute Cian O Donoghue
    Favourite Cian O Donoghue
    Report
    May 21st 2017, 1:27 PM

    @kevin: They did that in Oz actually.

    1
    Install the app to use these features.
    Mute Negan
    Favourite Negan
    Report
    May 20th 2017, 8:05 PM

    Great to see the economy back in action !

    27
    Install the app to use these features.
    Mute Alois Irlmaier
    Favourite Alois Irlmaier
    Report
    May 20th 2017, 10:22 PM

    Thnks to Noonan???

    9
    Install the app to use these features.
    Mute Gary Dorrian
    Favourite Gary Dorrian
    Report
    May 21st 2017, 9:35 AM

    There is a lot of comments that would be getting red thumped today.

    3
Submit a report
Please help us understand how this comment violates our community guidelines.
Thank you for the feedback
Your feedback has been sent to our team for review.
JournalTv
News in 60 seconds