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THE UK HAS approved the use of Pfizer’s Covid-19 antiviral after it was found to help prevent the virus from multiplying in at-risk sufferers.
The Medicines and Healthcare products Regulatory Agency (MHRA) approved a potentially “life-saving” treatment called Paxlovid for use among adults who could be vulnerable to Covid-19 due to age, weight or a prior chronic illness.
The regulator found the drug – which can be taken at home – to be safe and effective at reducing the risks of being admitted to hospital and death in people with mild to moderate infection and who are also at an increased risk of developing severe disease.
In a clinical trial in high-risk adults with symptomatic coronavirus infection, it was found to reduce the risk of being admitted to hospital and of death by almost 90%.
British Health Secretary Sajid Javid said the UK is “one of the first in the world to approve this life-saving antiviral”.
“We are also leading the whole of Europe in the number of antivirals we’ve bought per person – with over 2.75 million courses of this antiviral secured for NHS patients by the Antivirals Taskforce.
“The booster campaign, testing and antiviral defences ensure our country is in the strongest possible position to deal with the threat posed by Omicron as we head into the new year.”
Developed by Pfizer, Paxlovid is an antiviral medicine with a combination of active ingredients, PF-07321332 and ritonavir, that works by inhibiting a protease required for virus replication.
This prevents it from multiplying, keeping virus levels low and helping the body to overcome the viral infection.
The two active substances of Paxlovid come as separate tablets that are packaged together and taken together, twice a day by mouth for five days.
Dr June Raine, MHRA chief executive, said: “Today we have given our regulatory approval for Paxlovid, a Covid-19 treatment found to cut Covid-19 related hospitalisations and deaths by 89% when taken within three days of the start of symptoms.
“We now have a further antiviral medicine for the treatment of Covid-19 that can be taken by mouth rather than administered intravenously.
“This means it can be administered outside a hospital setting, before Covid-19 has progressed to a severe stage.
“I hope the announcement today gives reassurance to those particularly vulnerable to Covid-19, for whom this treatment has been approved. For these individuals, this treatment could be life-saving.”
Based on the clinical trial data, MHRA said it had found Paxlovid is most effective when taken during the early stages of infection.
As such, it recommends its use as soon as possible and within five days of the start of symptoms.
It has been authorised for use in people aged 18 and over who have mild to moderate Covid-19 infection and at least one risk factor for developing severe illness.
Risk factors include obesity, being over 60, diabetes mellitus, or heart disease.
Ben Osborn, country manager at Pfizer UK, said the “at-home therapy, shown in clinical trials to reduce hospitalisations and save lives, has the potential to lessen the devastating impact of a virus that has now taken over five million lives globally”.
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I’m applying for that. So should every one on jobseekers.
Plus expenses and pension, who do l give my cv to.
Forgot l don’t know the right person that holds the tickets to the gravy train.
Considering you couldn’t figure out where to send your CV I doubt you not knowing the right people would have been the deciding factor in you not getting the job.
Mursh, if you know the right people, you don’t need to send a C.V.
Whos been doing the job for the last 5 months?? & why dont they just keep doing it, and save some money!
Maybe someone who just qualified for the top up pension and doesn’t need the job anymore. Happens in the public sector all the time.
Who or what is a whos?
Jobsbridge? Be great to validate this wonderful govnt idea
Handy number!!
Ye..O’Brien did a three day week while living in the UK.
Why do they need 3 Commissioners to run it? It allows for buck passing which is what they did when they fu(ked up the crazy buggung story. Appoint one person to run it and the buck stops with him/her.
A nightmare job if you attempted to do it properly!
Is it bad that that would be a significant paycut for most people I know professionally….
Drew – You can finally come home “from China” ?
Or is that Wicklow that you are really living in ?
Monopoly money dosen`t count drew….
The usual moaners on here moaning. Moaners will moan about anything, they will even moan about having nothing to moan about.
I’ll do it for half
have your say