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Column A vaccine could soon be here for one of the most devastating diseases on the planet

With malaria causing 627,000 deaths last year, there are high hopes for the first vaccine. But old-fashioned people power can also make a difference.

WORLDWIDE, MORE THAN 200 million people are infected with malaria every year, according to the World Health Organisation (WHO). Last year, malaria caused an estimated 627,000 deaths globally – mostly babies and young children in the poorest countries in Africa.

Malaria is truly a disease of poverty. It affects poor people disproportionately, as they tend to live in malaria-prone rural areas and in houses that offer little protection against mosquitoes. And malaria also fuels poverty, as it slows economic growth and worsens other disease burdens, particular HIV and Aids.

But there is good news on the malaria front. The number of malaria deaths has almost halved since 2002, according to the latest edition of the World Malaria Report. From 2000 to 2012, the number of reported malaria cases fell by 29 per cent, thanks to the mass distribution of mosquito nets, public awareness campaigns and quicker diagnosis methods, allowing for faster treatment.

In Zanzibar, for instance, the number of malaria cases has dropped dramatically in just eight years. In 2005, infection rates on the island stood at 40 per cent, but last year, it had managed to bring that number down to below 1 per cent. The Zanzibar government now aims to completely eradicate the disease by 2017. Whether it will achieve that will depend not just on political will or funding; it also depends on the parasite responsible for the disease.

Research into the disease is not keeping up with demand

Scientists point out that the current strategy is threatened by “the lack of insecticide classes available for public health and the emergence of resistance to the majority of existing insecticides.”

The market for public health pesticide products is seen as risky and too small to warrant commercial investment, compared to the market for agricultural insecticides. As a result, there have been no new active ingredients in malaria treatment available to the general public in over 30 years.

This is now set to change. Researchers in seven African countries are involved in testing the world’s first malaria vaccine, developed by British pharmaceutical company GlaxoSmithKline, with funding from the Bill and Melinda Gates Foundation. The company is seeking permission to sell the vaccine, provisionally known as RTS,S, after the largest ever drug test in Africa showed it reduced infection rates among children by half.

The company has promised that the vaccine will be sold at a price only marginally above production cost, and that the surplus will be reinvested in further research on malaria. And such research is needed, as GlaxoSmithKline itself has indicated that the vaccine does not have the hoped-for universal applicability and impact. (Bill & Melinda Gates)
Focusing on people, not just technology

But the solution need not come from technology alone. One of the key findings of decades of work by governments and development organisations is that simple measures work. Sleeping under insecticide treated nets, for instance, can reduce overall child mortality by 20 per cent. UNICEF estimates that bed nets can save approximately six children’s lives per year for every one thousand children sleeping under them.

There isn’t a ‘one size fits all’ method

Not getting bitten is obviously the best protection. Malaria is transmitted exclusively through the bites of Anopheles mosquitoes, which only bite at night or in the early morning. Transmission is more intense in Africa, where the mosquitoes’ lifespan is longer, and where they prefer to bite humans rather than animals.

Anopheles mosquitoes breed in water. Countries that have improved sanitation and reduced the occurrence of stagnant pools of water have managed to bring down infection rates, but Anopheles mosquitoes breed in such a variety of situations that it is practically impossible to remove suitable habitat for the mosquito. A better strategy, therefore, is to combine approaches based on our knowledge of the biology of the mosquito, the epidemiology of the parasite, and focused on changes in human behaviour.

Aid agencies have learned that there is not a “one size fits all” method for the fight against malaria. Unless local people, local authorities and local health care practitioners are involved in a coordinated way, and unless communities have access to trained, properly remunerated technical experts, the fight against malaria will not be won.

Bringing health systems to marginalised communities

In many developing countries, there simply are not enough health workers to respond to the needs of all rural communities. Programmes funded through overseas aid can make an enormous difference in such contexts, by bringing high-quality rapid diagnostic tests (RDTs) for malaria to marginalised people and by training frontline health workers to diagnose and treat patients for common diseases such as malaria, pneumonia and diarrhoea.

Aid agencies also help train people to diagnose and treat of malaria at home. Early diagnosis prevents deaths and should be a core part of any strategy to fight malaria. NGOs, therefore, typically bring together community volunteers, mothers, village leaders, traditional healers, and health workers to help them learn about, and take action against, malaria.

But knowledge is not the only major barrier to an effective anti-malaria strategy. For many poor communities, the medicines are simply too expensive, and the local health centres simply too far away, to be a real option. In many communities, aid agencies have helped set up village solidarity funds, funded by contributions from villagers and used to subsidise the transportation of young children with serious malaria or other health concerns.

A grass-roots approach to malaria control

What NGO work in countries like Zambia, Benin and Senegal is showing is that this approach is working. While many aid donors emphasise the importance of new drugs, the grass-roots approach to malaria control works with communities and families to help them recognise the symptoms of malaria and to ensure that even the poorest and most vulnerable members of society have access to medicines and bed nets.

Both approaches meet in the middle, through the coordination by national governments. And if anything, that is the vital ingredient for the international fight against malaria: the realisation that local governments and local solutions must always be at the heart of any programme aimed at ending disease, hunger and poverty.

Hans Zomer is the Director of Dóchas, the network of Ireland’s Development NGOs. Dóchas publishes the World’s Best News, a news service initiative from Irish NGOs which aims to highlight positive news stories from around the globe. Visit the World’s Best News on Facebook or worldsbestnews.tumblr.com for more information.

Read: Cases of malaria in Ireland rise for the third year in a row

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    Mute Éanna o Sca
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    Feb 21st 2024, 3:15 PM

    It’s a NO from me!

    324
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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:05 PM

    “STRIVE TO SUPPORT”

    ” DURABLE RELATIONSHIP”

    Apart from the legal eagles that must love this vague nonsense ( lime a €€ jackpot )there’s nothing in there to say me to the yes side.

    A BIG NO/NO from me

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:06 PM

    @Ken Mc Carthy: ‘sway’ me!!! even

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    Mute Brendan O'Brien
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    Feb 21st 2024, 3:44 PM

    @Ken Mc Carthy: How about ‘lime a €€ jackpot’? Some kind of code?

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:53 PM

    @Brendan O’Brien: hey hey…. I was waiting on the ‘dyslexia’ mocking— 4 minutes!!! U getting slow

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    Mute Brendan O'Brien
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    Feb 21st 2024, 3:55 PM

    @Ken Mc Carthy: You’re saying you have dyslexia?

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:58 PM

    @Brendan O’Brien: it doesn’t bother me one iota/ never hindered my career or life— its other small minded idiots that seem to have the problem with it!

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    Mute Brendan O'Brien
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    Feb 21st 2024, 4:00 PM

    @Ken Mc Carthy: I’ll stick to mocking your hero-worship of Trump and such things in future.

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    Mute George Vladisavljevic
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    Feb 21st 2024, 3:52 PM

    What qualifies as durable?

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:59 PM

    @George Vladisavljevic: no idea but you have to ‘strive to support’ it

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    Mute Brian Hunt
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    Feb 21st 2024, 4:04 PM

    @George Vladisavljevic: Well, you could have a durable relationship with your doctor, dog, grocer or your local handyman!

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    Mute Seanie
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    Feb 21st 2024, 4:19 PM

    @George Vladisavljevic: Thomas Byrne FF on upfront with Katie Hannon Monday night was asked this in a debate with peader Tobin of Aontu, he hadn’t got a jot and tried bluffing his way through the answer, Tobin ran rings around him.

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 5:06 PM

    @Seanie: I was watching that……like seriously……Thomas byrne was the best they could put ‘out to bat’?? Tobin didn’t even have to try very hard…….. byrne scored plenty of own goals

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    Mute silvery moon
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    Feb 21st 2024, 7:45 PM

    @George Vladisavljevic: the durable bunny

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    Mute M G
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    Feb 21st 2024, 4:30 PM

    (Vote NO) to this lieing government they have gone rogue deliberately trying to feed misinformation to the Irish people to get a yes vote it NO .and if they try to get it passed a second time it will be NO again.

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    Mute Soundy Sound
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    Feb 21st 2024, 3:23 PM

    I think this referendum will very well display that the loud, vocal, right wing commentary as seen in the comments section of the journal are not at all representative of the views of the general population. It’s all, no/no on here but this referendum will easily pass.
    Empty can makes most noise!

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    R B
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    Mute R B
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    Feb 21st 2024, 3:38 PM

    @Soundy Sound: if it does easily pass I would be very worried for the critical thinking of the nation.

    I don’t see it passing but it depends on the profile of the turnout. Unfortunatly we have ppl who will just vote for whatever the govt say without looking at what being asked to vote for.

    Your constitution is the last protection against government overreach. Unless you are 100% certain of what the change will cause it should always be a no vote.

    When you can’t define durable it opens potential legal chaos for absolutly no reason at all.

    Senator Michael McDowell have all spoken very well on this as an ex min for justice and AG he is very well placed to do so. An honest man in my view.

    I would urge anyone unsure to look at his 8 page document on it and why it should be No/No.

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    Mute Éanna o Sca
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    Feb 21st 2024, 3:38 PM

    @Soundy Sound: were you not watching the news last night? no side zero coverage, obviously a governmental ploy.

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:38 PM

    @Soundy Sound: more likely than not this referendum will pass as its got all government parties pushing it, a quango set up & paid to push it ( electoral commission), media fully behind the government mantra of a ‘yes’ vote & the ( not even) subtle dictat that if we don’t bring in the correct result we’ll have to go again. The legal profession see this as a goldmine for sure but you’re wild accusation of labeling anyone who opposes this being rammed through as the ‘far right’ just once again shows how that term ( far right) has become so diluted & misused as to make it a worthless insult

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    Mute Éanna o Sca
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    Feb 21st 2024, 3:39 PM

    @R B: I just do with what the govt demand us to do!

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    Mute Éanna o Sca
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    Feb 21st 2024, 3:39 PM

    @Éanna o Sca: I just do the opposite of what gov demand us to do*

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    Mute Brendan O'Brien
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    Feb 21st 2024, 3:42 PM

    @Ken Mc Carthy: A Trump supporter balking at the term ‘far right’ – LOL etc.

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    Mute jiminybillybob
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    Feb 21st 2024, 3:47 PM

    @R B: what critical thinking, a nation of sheep it is.

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:52 PM

    @Brendan O’Brien: hi Kevin….adults are talking here…. give mommy back her phone

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    Mute silvery moon
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    Feb 21st 2024, 7:48 PM

    @Soundy Sound: if it does pass don’t bother with the mother’s day card after voting the only mention of her out of the constitution a big NO/NO from me

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    Mute Marie McPhillips
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    Feb 21st 2024, 10:53 PM

    @R B: Senator McDowell on YouTube also. He’s excellent

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    Mute martin finnegan
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    Feb 21st 2024, 7:19 PM

    Voting no to both

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    Mute Mark Rooney
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    Feb 21st 2024, 3:36 PM

    Sinn fein will re run it if they get into government if the Yes vote fails to go through….They reckon they can reword it to sway a Yes vote

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    Mute Ken Mc Carthy
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    Feb 21st 2024, 3:42 PM

    @Mark Rooney: well, there’s something to be said for that approach….. the vague makey uppy present wording is wide open to different interpretations & legal challenges. A bit of clarity would go a long way to swaying me over to the government mantra (a ‘yes’ vote)

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    Mute Magnificent Mongoose
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    Feb 22nd 2024, 9:05 AM

    @Mark Rooney: Sinn Féin are doing their best to not be in government. They are the worst opposition party I have ever seen.

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    Mute Padraig O'Brien
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    Feb 21st 2024, 4:14 PM

    What if your relationship on durex?

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