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Annette Page, left, and her sister Sharee Page, attend treatment together. Rick Bowmer

"Had she not been diagnosed, I don't think I would have caught mine."

The sisters fighting cancer together.

TWO UTAH SISTERS who grew up in the same bedroom, went to the same college, worked for almost a decade at the same company and have visited over 50 countries side by side.

Now every three weeks, they sit together in matching chairs and chat as their bodies are pumped full of chemotherapy drugs.

Sharee Page, 34, and Annette Page, 36, were recently diagnosed with breast cancer within about two weeks of each other, a coincidence that doctors say is extremely rare. But that coincidence has meant they can face the disease like they have nearly every other aspect of their lives— as a team.

“Wow, talk about a huge blessing,” said Annette Page, who lives five minutes from her sister in northern Utah.

Who gets to go through something so hard with their best friend, their sister?

The Page Sisters, as some of their friends like to call them, found out soon after their diagnosis that they have the BRCA2 gene, a mutation that puts a woman at a much greater risk for breast and ovarian cancers.

BRCA mutations, which stands for breast cancer susceptibility gene, are most commonly found in women of Ashkenazi Jewish descent, although some northern European populations also have a higher risk of inheriting one of the mutated genes.

Annette Page, Sharee Page The “Page Sisters,” as some of their friends like to call them, were recently diagnosed with breast cancer within about two weeks of each other. Rick Bowmer Rick Bowmer

Adam Cohen, a doctor at the University of Utah’s Huntsman Cancer Institute, said the gene can increase the risk of breast cancer tenfold. But Cohen said he has never seen two siblings diagnosed within weeks of one another.

“It’s not uncommon to have somebody with breast cancer and BRCA2 mutation and whose sibling develops breast cancer,” he said.

But doing it within two weeks is certainly very uncommon.

In late March, after discovering a large lump in her left breast, Annette Page was diagnosed with Stage 3 breast cancer. The news prompted Sharee Page to get herself checked, and the same doctor soon diagnosed her with Stage 2 breast cancer.

“Had she not been diagnosed, I don’t think I would have caught mine for six months to a year,” Sharee Page said.

Every few weeks, the sisters meet at their mother’s house so that she can drive them to their chemotherapy appointment at Davis Hospital. After the six-hour session, they experience a myriad of matching chemo side effects, including nausea, bloody noses, neuropathy and headaches.

Sharee Page Sharee Page got herself checked after her sister was diagnosed. Rick Bowmer Rick Bowmer

Their bodies react to the medicine in a nearly synchronised fashion. Both are unable to eat food for almost two weeks. Exactly 10 days after treatment, they break out in a rash.

“It’s nice to know that someone knows exactly what you’re going through,” Sharee Page said.

The women, who are part of a devout Mormon family, have four other siblings. One of their sisters also recently tested positive for the BRCA2 gene. But she does not have cancer, so she plans to get a double-mastectomy.

Cohen said that course of preventative treatment is sometimes recommended for someone who has the mutation and is cancer free. Actress Angelina Jolie, for instance, had a double mastectomy and her ovaries removed after testing showed she carried a similar mutation.

Annette Page, Sharee Page The two women react to their treatment in almost exactly the same way. Rick Bowmer / PA Images Rick Bowmer / PA Images / PA Images

The family has a long history with breast cancer, as the sisters’ grandmother and great-grandmother both died of the disease.

The siblings’ mother, Susan Page, is a survivor of throat and mouth cancer who also has the BRCA2 gene. She said she cried for days after she found out that two of her children had cancer.

You spend your whole life, even before they’re born, trying to protect them and make sure they’re safe and try to keep them healthy. And then something like this happens.

The sisters now go to the same doctor for joint appointments, and they help each other get through the especially difficult days. When Sharee Page’s hair started falling out soon after she started chemo, Annette Page shaved it all off for her.

But their nearly identical treatment plans may soon deviate. Annette Page’s cancer has spread to her lymph nodes, so unlike her sister, she will have to undergo radiation therapy next.

Read: Calls for a new emergency health fund to pay for expensive cancer drugs >

Read: ‘Time is running out’: John Crown says cancer patients could die over delay in accessing drug >

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9 Comments
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    Mute Luke Sullivan
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    Dec 14th 2013, 3:35 PM

    Phew, at least it there not recalling the preparation H, and ‘Fire in the hole’ anal itch cream I ordered from them for herself for Xmas.

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    Mute Ann Mc Kennedy
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    Dec 14th 2013, 3:38 PM

    Lucky woman your missus!!

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    Mute Luke Sullivan
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    Dec 14th 2013, 3:40 PM

    I’m thoughtful. As Confucius says, ‘they who go to bed with itchy bum, wake up with smelly finger’.

    Plus, it was 50% off.

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    Mute Ann Mc Kennedy
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    Dec 14th 2013, 6:47 PM

    Bit of an ass fixation going on!?!

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    Mute Luke Sullivan
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    Dec 15th 2013, 12:52 AM

    No, I got her vagisil too.

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    Mute Ann Mc Kennedy
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    Dec 15th 2013, 1:05 AM

    You have to be the most thoughtful husband ever!! I hope she appreciates it!!!

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    Mute Laura W
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    Dec 14th 2013, 4:34 PM

    My pharmacist told me that children’s cough medicines aren’t available here anymore, something about them being proved ineffective in under 12s? Please correct me if I’m wrong, it’s just that when I saw this article I thought, “Well that doesn’t pertain to children in Ireland”. I’d like to know for sure because my mother (who is from the UK) suggested that I buy this Tixilix stuff for my daughter.

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    Mute Jeanniejampots
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    Dec 14th 2013, 4:42 PM

    No Laura you are right. Pharmacies here are not allowed to sell cough bottle to kids under 6 ( not 12) as they are not proven to work and have been proven to potentially have dangerous side effects. If these products are sold here they must have no active ingredients so are not cough bottles but not sure if you can even get them here.

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    Mute Jenni Sheridan
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    Dec 14th 2013, 7:38 PM

    That’s not true, you can get cough medicines for children here suitable from 2 years and upwards, the age recommendation on certain medications was changed from 2 to 6 years, not all of them.

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    Mute Jenni Sheridan
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    Dec 14th 2013, 7:59 PM

    In actual fact, there are a couple that are suitable from about 6 months onwards also.

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    Mute Hayley Murphy-Farrell
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    Dec 14th 2013, 11:23 PM

    There’s a throat syrup you can get for babies and children called Pharmony, but it’s just natural ingredients.

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    Mute Jenni Sheridan
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    Dec 15th 2013, 12:14 AM

    That’s right Hayley, its suitable from four months and contains glycerine, aniseed and lemon.

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    Mute RossMcEntegart
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    Dec 15th 2013, 12:39 PM

    Completely irrelevant article: not one of those Tixylix products is currently available in Ireland!

    For those debating what can and cannot be used by kids of what age, follow the link to the other story at the bottom of the article.

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