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Spinal tap test could detect Parkinson's disease a lot earlier. Shutterstock

Spinal fluid test could give early diagnosis of Parkinson's disease

The first signs of having the disease include body tremors, but this new test could give a diagnosis before symptoms present.

TESTING FOR PROTEIN biomarkers in spinal fluid could show up the early stages of Parkinson’s disease, giving an early diagnosis, a study has found.

New research by the Perelman School of Medicine researchers at the University of Pennsylvania has found that people with early Parkinson’s had lower levels of amyloid beta, tau and alpha synuclein in their spinal fluid.

Symptoms

Those with with low levels of amyloid beta and tau were more likely to have the postural instability-gait disturbance- dominant (PIGD) motor type of disease. This form of the disease can cause those who have the disease to fall and walking can be difficult.

The study, which was published in JAMA Neurology, came from the five-year Parkinson’s Progression Markers Initiative (PPMI). Spinal taps were carried out on 102 participants.

Of those that took part in the study, 63 people either had early and untreated Parkinson’s disease. The tests were compared to 39 individuals unaffected by the disease.

Parkinson’s progression

Protein bio-markers were found to be low in those suffering from the disease which researchers stating it could be key in further research on how Parkinson’s progresses.

ScienceDaily.com reports that Dr. John Trojanowski, director of the Penn Udall Center for Parkinson’s Research said that “early prediction is critical, for both motor and dementia symptoms.

This spinal fluid testing procedure is only being used in research studies at the moment and will be evaluated in a larger study at a later date.

Read: ‘Human brain cells in mice’ technique could help tackle Parkinson’s>

Read: 8 reasons to be excited about the new Michael J. Fox show>

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6 Comments
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    Mute a
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    Dec 13th 2020, 11:24 AM

    Why is it on us? We can’t control the amount of packaging these days. Guess who can? Oh yeah!-the conpanies who package their goods. Deal with them.

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    Mute Jim Smith
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    Dec 13th 2020, 11:45 AM

    @a: Totally agree that we should hold these companies accountable. I’ve even written to some companies in relation to this.

    However, we can also have a huge impact by not buying products with wasteful packaging. If we don’t buy the products, they won’t keeping making them.

    We should also buy more local and second hand products. Charity shops are great for Christmas shopping.

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    Mute The world outside the M50
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    Dec 13th 2020, 12:39 PM

    @a: Exactly, you will see ‘My M&S’ ‘My this’ & ‘My That’ but when it comes down to it you will also see ‘YOUR WASTE’ – yourwaste.ie
    They don’t want the waste yet they allow it to be produced.

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    Mute Sean Baylon
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    Dec 13th 2020, 3:59 PM

    @a: I wrote to my local TD (a green party TD) and never received any response but this was the gist of it. More expensive everyday items you buy in the likes of Dunnes generally (but not always) comes in packaging that is recyclable- stuff such as apples etc. But your same lower priced items in Lidl/Aldi etc do not and it’s this that is making a difference. There is also confusion amongst many between the difference of ‘made from recycled material’ and ‘recyclable material’ it confuses most and the packaging can be difficult to discern based on that. The onus should be on suppliers/packaging companiez/sellers and government to make it impossible to sell in non recyclable material.

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    Mute Dangling Damo
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    Dec 13th 2020, 11:33 AM

    No convenient recycling facilities available for polystyrene so this still goes into the general waste. Only lip service from companies to reduce reuse recycle but the consuner gets the blame

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    Mute John Considine
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    Dec 13th 2020, 3:18 PM

    @Dangling Damo: Even though most of the bin collectors don’t allow it they will actually separate it in the recycling center. It’s purely a cost thing so it’s not a heinous crime like including wet waste or something which can mean an entire trucks worth of recycling is ruined.

    I try to avoid such packaging when I can but I don’t feel one bit bad about sending it off in the bin when I do happen to need to get rid of some and I don’t have enough other stuff to justify a run to a bring site.

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    Mute JillyBean
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    Dec 13th 2020, 11:40 AM

    Limit your contacts,
    Limit your travel ,
    Limit your waste ,
    Sure why don’t I limit oxygen aswell while I’m at it this Christmas

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    Mute Shane McGrath
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    Dec 13th 2020, 2:04 PM

    @JillyBean: You could

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    Mute Caroline Otoole
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    Dec 13th 2020, 11:50 AM

    Selection boxes drive me mad. Complete waste of cardboard and plastic.

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    Mute Jim Smith
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    Dec 13th 2020, 12:05 PM

    @Caroline Otoole: Absolutely right. Yet people still buy them and blame the companies who make them for the waste.

    Kids don’t care about the box. Just buy a few chocolate bars instead.

    67
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    Mute Conrad Shields
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    Dec 13th 2020, 12:37 PM

    @Caroline Otoole: Not just that they are packaged using cardboard and plastic, they make the packaging oversized to make it appear you are getting more than you actually are, an even bigger waste.
    I am less concerned about the cardboard, but the plastic needs to be removed.
    If the Govt implemented a returns process for that kind of plastic (like 10c per pack) going back to the point of purchase, those shops would then put pressure on suppliers to produce without the plastic.
    Got a package from Amazon this week that would usually be wrapped in a box or plastic bag, but this came in a paper bag. It can be done.

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    Mute Jane
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    Dec 13th 2020, 12:59 PM

    @Conrad Shields: actually saw a post on twitter during the week about this. It was a photo of the packaging alongside the bit of chocolate thats in one. It was quite jarring.

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    Mute Jonnie Marre
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    Dec 13th 2020, 2:59 PM

    @Caroline Otoole: totally agree! Over sized packaging!! I don’t buy selection boxes for this reason

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    Mute Dick Barrett
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    Dec 13th 2020, 1:26 PM

    I am calling on all journal readers to boycott these polls until a serious controversial topic is put up for discussion. The odd seasonal topic is OK, but not a relentless diet of them.

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    Mute SteveBuzzard
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    Dec 13th 2020, 12:04 PM

    I made a perfectly valid point and was censored by the moderator.

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    Mute David Corrigan
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    Dec 13th 2020, 12:18 PM

    @SteveBuzzard: I believe the moderator is fond of a box of After Eights. Do you see where I am going with this? :-)

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    Mute Sam Glynn
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    Dec 13th 2020, 1:58 PM

    Celebrating with my parents this year, thankfully, and they live in a zero waste household so I have no choice.

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    Mute Teresa O'Donnell-Joyce
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    Dec 13th 2020, 1:04 PM

    Make up gift sets and perfume packaging are the worst offenders next to children’s toys. I’m trying as best I can to avoid buying them. It’s not easy though.

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    Mute Jim Smith
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    Dec 13th 2020, 1:12 PM

    @Teresa O’Donnell-Joyce: Keep it up. All we can do is our best. We just need to be conscious consumers.

    Consider making your own gift sets with individually selected products instead of prepackaged sets. It’s a much more thoughtful gift. It’s not easy and takes extra time of course. I understand that sometimes it’s just not an option.

    Good luck with the Christmas shopping.

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    Mute Teresa O'Donnell-Joyce
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    Dec 13th 2020, 1:21 PM

    @Jim Smith: My family will be given home baking gifts. Shame about my dodgy baking skills. It’ll be fun.

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    Mute emer daly
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    Dec 13th 2020, 1:36 PM

    Yes I won’t be buying as much food this year like tins of sweets crisps biscuits etc. Wasted do much ladt year
    Will buy some nice crackers cheese and maybe some nice meats to go with.

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    Mute Gerard Heery
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    Dec 13th 2020, 2:39 PM

    Stove ,free heat ,end of story.

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    Mute Lisa Saputo
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    Dec 13th 2020, 2:15 PM

    I’m bought three rolls of wrapping paper last year, and I am still using it. But then again, the gifts weren’t huge to wrap.

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    Mute Neil Reilly
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    Dec 14th 2020, 5:07 PM

    @Lisa Saputo: gift bags are handy as you can reuse them next year once you don’t write on the tag

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    Mute 011Y
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    Dec 13th 2020, 3:30 PM

    Moderator doesn’t like musical notes either. We’ll it’s their loss. It was a a wonderful comment;-)

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    Mute Garreth Byrne
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    Dec 13th 2020, 8:24 PM

    and if people cannot limit their waste by eating and drinking moderately, they can recycle personal waste by using a compost lavatory.

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    Mute Jim Lingk
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    Dec 13th 2020, 7:06 PM

    No

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    Mute Siobhán Kirby
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    Dec 14th 2020, 5:57 PM

    I can’t be ars@d to wrap gifts, so this poll is perfect for me. I just used gift bags, that my Mammy saves and reuses the next Christmas!! We have been doing are bit for ages and didn’t even know it. Lol

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    Mute Siobhán Kirby
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    Dec 14th 2020, 5:56 PM

    I can’t be ars@d to wrap gifts, so this poll is perfect for me. I just used gift bags, that my Mammy saves and reuses the next Christmas!! Lol

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