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Researchers find elusive European parent of lager yeast in Ireland

Researchers at UCD discovered and isolated S eubayanus in a wooded area of their campus.

FOR THE FIRST time in Europe, scientists have discovered the ancestor of the yeast species necessary for the production of lager beer.

Brewing is one of the oldest human industries, and scientists have uncovered evidence of fermented beverages from China from at least 7,000 years ago, and from Israel from up to 13,000 years ago.

Modern brewing developed in Europe, where, until the Middle Ages, most beer brewing was associated with a yeast called Saccharomyces cerevisiae.

Today this species of yeast is still used to make ale-style beer, wine and bread.

However, most beer made nowadays is lager, not ale, and there is a lot of interest in understanding the historical shift from one to the other.

Lagers are fermented using a bottom fermenting yeast at cool temperatures, while ales are fermented with a top fermenting yeast at much warmer temperature.

Lager brewing, which first appeared in the 13th century in Bavaria, uses a different species of yeast, Saccharomyces pastorianus.

This is a hybrid of two parents, only one of which is S cerevisiae.

Until 2011, the identity of the second parent was a mystery, when Saccharomyces eubayanus was discovered in the Patagonian Andes in South America.

Like S pastorianus, S eubayanus is cold-tolerant.

While records show the first use of S pastorianus was in breweries in southern Germany, the S eubayanus parent was never found in Europe.

Instead, researchers have discovered the yeast in South America, North America, China, Tibet, and New Zealand.

This caused some researchers to wonder whether S eubayanus had, in fact, ever been in Europe, and, if not, where the lager yeast S pastorianus had come from.

But now researchers at UCD discovered and isolated S eubayanus in a wooded area of their campus.

The researchers isolated two different S eubayanus strains from soil samples collected on the Belfield campus of University College Dublin, as part of undergraduate research projects to identify wild yeasts and sequence their genomes.

The samples come from soil on two sites on the university campus, about 17 metres apart, collected in September 2021.

According to the study, the genome sequences of these two isolates showed that they are related to the ancestral S eubayanus strain that initially mated with S cerevisiae to form S pastorianus.

Researchers say the discovery of S eubayanus in Ireland shows that this yeast is native to Europe and it seems likely that it has lived in other parts of the continent.

This new study supports the view that there were natural populations of the yeast in southern Germany in the Middle Ages and these provided the parents of the first lager yeast.

The paper’s lead author, Geraldine Butler, University College Dublin, said: “This discovery is a fantastic example of research-led teaching.

“Our undergraduates have found more than a hundred yeast species in Irish soil samples over the past five years, and we’re delighted to stumble across S. eubayanus on our own doorstep.

“We’re hoping to find a commercial partner to brew with it so we can find out what it tastes like.”

The research is published in FEMS Yeast Research.

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    Mute John Magee
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    Dec 7th 2022, 8:06 AM

    It’s a 2nd cousin yeast to the Sally O Brien-ius, [and the way she might look at yeh]

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    Mute Daniel O'Connor
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    Dec 7th 2022, 8:51 AM

    @John Magee: what are you harping on about ???

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    Mute SPQH
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    Dec 7th 2022, 9:13 AM

    @Daniel O’Connor: at yeast he’s not hoping mad!

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    Mute Dave Connolly
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    Dec 7th 2022, 8:21 AM

    Sorry. Had to stop in the woods for a Jimmy on way home from the pub.

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    Mute Marcus Suridius
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    Dec 7th 2022, 8:07 AM

    Of course it would be found here.

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    Mute Brian Lenehan
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    Dec 7th 2022, 9:06 AM

    Well, I don’t like to be a skeptic, but…
    UCD campus is landscaped to the hilt. In all likelihood the soil is made-up, as in its top-soil that is brought in from elsewhere off-campus to fill in the gaps. It just doesn’t strike me as plausible.

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    Mute Rob Goodbody
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    Dec 7th 2022, 11:19 AM

    Are any lagers live? One student spilling a can or throwing up could explain a lot.

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    Mute James A. O'Donoghue
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    Dec 7th 2022, 1:40 PM

    @Rob Goodbody: or taking a piss after a scoop full….

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    Mute Tom Hogarty
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    Dec 7th 2022, 10:11 AM

    Researchers are doing all sorts of amazing things, the last time one caught my attention was by a guy I knew from Germany who did his doctorate on Prostition on the Reeperbahn. Well, educators do recommend that you should really like whatever it is you have chosen to study in such detail.

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    Mute Tom Hogarty
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    Dec 7th 2022, 10:12 AM

    @Tom Hogarty: Prostitution (sp)

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